Inverted papilloma of the nasal cavity and paranasal sinuses is an uncommon benign lesion in which there is inversion of the neoplastic epithelium into the underlying stroma. Nowadays, some have suggested for the human papillomavirus a potential etiologic role in pathogenesis of inverted papilloma. The tumor's local aggressiveness, high rate of recurrence, associated malignancy, and tendency to multicentricity have led to the advocation of radical surgical removal of the tumor. Of 14 patients with inverted papilloma of the nasal cavity and paranasal sinuses diagnosed between 1987 and 1991, 11 were treated with surgery. The results are as follows : 1) The ratio of males to females was 3.7:1, the peak incidence was in the fourth decade of life, and the average age of patients was 45 years. 2) The most common presenting symptom was unilateral nasal obstruction followed by rhinorrhea, postnasal drip, epistaxis, hyposmia, and headache. 3) The symptoms varied in duration from several months to 30 years. Nine patients(64%) had symptoms for three years of less. 4) Six patients(43%) had previous nasal surgery. Most of these operations consisted of polypectomies or Caldwell-Luc operation. 5) The most common radiographic finding was a unilateral nasal mass with opacification of the adjacent maxillary sinus. Five patients showed evidence of bone destruction. 6) The most common site of origin of lesion was the lateral nasal wall. The most commonly involved sinus was the maxillary sinus(73%). 7) In the study group of 14 patients, 11 underwent a surgical procedure. Caldwell-Luc operation was performed in seven cases and lateral rhinotomy with medial maxillectomy in two cases. Recurrence was seen in one case.
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