Serological Study of the Head and Neck Cancers |
Gi Ryoung Kim, MD, Ki Woo Paik, MD, Won Chung, MD, and Jai Sun Kim, MD |
Department of Otolaryngology, Yonsei Cancer Center, Korea |
두경부악성종양의 혈청학적 연구 |
김기령 · 백기우 · 정 원 · 김재선 |
연세암센터 이비인후과 |
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ABSTRACT |
Ishigawa(1965) was certain that γ-globulin level in serum of the Wegener's granuloma was increased. More than that of normal person through experiment and Hashimoto(1968) reported the value of serum LDH was increased about 72.9%, Imaii also reported the increment of alkaline phosphatase isoenzyme, in cases of head and neck cancers. The author has been studied the change of serum contents such as γ-globulin, LDH and alkaline phosphatase in cases of head and neck cancers to consider the clinical significance and the pathogenesis as a preliminary study of the cancer, and the following results were
obtained : 1) LDH and alkaline phosphatase in serum are 974±149 unit and 2.53±2.275 SU. 2) Total protein is 728±0.57gm/dl and albumin, α1, α2, β and γ-globulin are 4.01±0.92gm/dl(55.08%), 0.25±0.066gm/dl(3.43%), 0.68±0.173gm/dl(9.34%), 0.73±0.161gm/dl(10.03%) and 1.61±0.41gm/dl(22.12%). In this study, only γ-globulin level is more increased than that of normal value and the significance for diagnosis of the head and neck cancers would be suspected.
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