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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 25(2); 1982 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1982;25(2): 229-35.
Effects of Topically Applied NaCl Crystals on Cochlear Microphonics of Guinea Pigs
Kwan Taek Noh, MD, and Ki Chul Shin, MD
Department of Otolaryngology, Seoul National University Hospital, Korea
NaCl 結晶이 Guinea Pig의 Cochlear Microphonics에 미치는 影響에 關한 硏究
盧寬澤 · 申基哲
서울大學校 醫科大學 耳鼻咽喉科學敎室
ABSTRACT

A series of experiments was performed to study the effects of NaCl crystals on cochlear microphonics(CM) after application of it to round window membrane of ten guinea pigs. Also effects of Ringer's solution was studied for control group on five guinea pigs. The stimulating tone was 1 KHz continuous pure tone of 90 dB intensity. CM were recorded from round window membrane with single electrode technique during 60 minutes at every 5 minutes. The results were as follows : 1) CM showed an initial overshoot, which showed 6.6% increase of original level. The peak of overshoot was noted 2 minutes after NaCl crystal application. 2) The overshoot was followed by primary rapid decrease. The output of the bottom of decrease was noted 15 minutes after NaCl crystal application, and showed 43.6% of original level. 3) After then, CM showed incomplete temporary recovery, which showed 65.2% of original level until 45 minutes after NaCl crystal application. 4) Then, second decrease of more moderate rate was noted. At 60 minutes, CM showed 58.2% of original level. 5) After application of Ringer's solution, CM showed initial rapid decrease. But after removal it, CM showed continuous recovery up to 87.4% of original level at 60 minutes after application.

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