Clinical Analysis on Transseptal Transsphenoidal Approach to Pituitary Gland

Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 27(6); 1984 > Article

Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1984;27(6): 579-83.

Yang Gi Min, MD¹, Bong Jae Lee, MD¹, Jin Young Kim, MD¹, and Hyun Jip Kim, MD

1;Department of Otolaryngology, 2;Neurosurgery, College of Medicine, Seoul National University, Korea

경비중격 경접형동 뇌하수체수술에 관한 임상적 연구

민양기¹ · 이봉재¹ · 김진영¹ · 김현집²

서울대학교 의과대학 이비인후과학교실1;신경외과학교실2;

ABSTRACT

42 patients were analyzed who had received transseptal transsphenoidal surgery on pituitary lesions from June 1977 to April 1984 at Seoul national university hospital. Of 42 cases, 35(83%) were functioning pituitary adenomas, 6 were nonfunctioning and 1 was CSF rhinrrhea. The predominent symptoms were amenorrhea and galactorrhea(26%), headache(24%) acral enlargement(21%) and disturbances of visual field(12%). Of 14 cases with preoperative visual field disturbance, 6 cases(43%) were improved with operation, and 32 cases(91%) of 35 functioning pituitary adenomas were improved endocrinologically. Surgical mortality was zero. Complications associated with operation were CSF rhinorrhea(4 cases ; 9.5%), transient diabetes insipidus(3 cases ; 7%) and each 1 case of meningitis, septal perforation, rhinitis sicca, total unilateral blindness and transient respiratory distress.