Behcet's syndrome is a chronic, often progressive disease, characterized by recurrent ulceration of the mouth and genitalia associated with iritis. This entity, originally confined to the above triad of symptoms, appears to by systemic disease manifested by skin lesion, thrombophlebitis, neurologic or visceral symptoms. The exact etiology of this syndrome has not been known. However, in recent years, many investigators suggested that autoimmune mechanism could be the cause of this disease. We could classify the Behcet's syndrome into 2 types, complete type which manifests 4 main lesions, oral, genital, skin and eye lesions, and incomplete type which manifests 3 of 4 lesions. This is a report of a case of complete type of Behcet's syndrome in a 19-year-old male with a good therapeutic result using antibiotic, steroid and antiviral agent and reviewing literature.