Epistaxis is commonly cited as symptoms of high blood pressure. However, the validity of this relation has not stated by clinical and pathological process. So, we compared the frequencies of epistaxis on the normotensive persons, hypertensive persons and of hospital patients with epistaxis. We also studied the pathological process of the vessels of nasal mucosa of the normotensive persons, hypertensive persons and of the hospital patients with epistaxis. The results of our studies were hypertension causes cavernous hemangiomatous proliferation of capillaries and venules of the nasal mucosa and causes worsened the nose bleeding but it does not causes epistaxis.