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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 32(5); 1989 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1989;32(5): 897-903.
Clinical Observation of Non-Hodgkin's Lymphoma in Head and Neck
Jin Hack Cho, MD, Kwang Yoon Jung, MD, Hyun Ho Lim, MD, and Hong Kyun Yoo, MD
Department of Otorhinolaryngology, Head and Neck Surgery, Collage of Medicine, Korea University, Korea
두경부 Non-Hodgkin's 임파종에 대한 임상적 고찰
조진학 · 정광윤 · 임현호 · 유홍균
고려대학교 의과대학 이비인후과학교실

The evaluation of a patient with a mass in the head and neck may require the consideration of lymphoma in the process of differential diagnosis. Non-Hodgkin's lymphoma(NHL) constitutes a diverse group of diseases with differences in natural history, response to therapy and prognosis. Unlike Hodgkin's disease where the pattern of spread appears to be via contiguous lymph node chains, in NHL the spread is non-contiguous. The high frequency of bone marrow involvement and frequent extranodal disease suggests early hematogeneous spread. Although cell surface marker study, which have recently become available, a classification proposed by Rappaport has been widely accepted and is based on a diffuse or nodular pattern of lymph node pathology, the type of malignant cell and degree of differentiation. The authors experienced 25 cases of clinically and pathologically diagnosed NHL in the head and neck from January 1983 to March 1989, and clinical observation and analysis were performed with review of literatures. 

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