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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 37(3); 1994 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1994;37(3): 449-53.
The Efficacy of Diatrizoate Meglumine(Hypaque<sup>®</sup>) Versus Steroids in Sudden Deafness
Byung Hoon Park, MD1, Hak Hyun Jung, MD1, Hyun Ho Lim, MD1, Jong Ouck Choi, MD1, Yong Bae Lee, MD2, Soon Yuhl Nam, MD2, and Won Il Kim, MD2
1;Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, 2;Department of Otolaryngology, Koryo General Hospital, Seoul, Korea
돌발성 난청환자에서 Diatrizoate Meglumine(Hypaque<sup>®</sup>)와 부신 피질 호르몬제의 비교 치료 효과
박병훈1 · 정학현1 · 임현호1 · 최종욱1 · 이용배2 · 남순열2 · 김원일2
고려대학교 의과대학 이비인후-두경부외과학교실1;고려병원 이비인후과2;

Sudden deafness is defined as an abrupt onset of sensorineural hearing loss without definite cause. Various medications, such as steroids, vasodilators or diatrizoate meglumine(Hypaque), have been suggested as treatment models for sudden deafness. The purpose of this study was to evaluate the therapeutic effect of the diatrizoate meglumine versus steroids on 49 patients(54 ears) with sudden deafness. Fifty-four ears were divided into the diatrizoate meglumine-treated group(18 ears), steroid-treated group(30 ears), and control group(6 ears). The recovery rates were 56%, 53%, and 67% in diatrizoate meglumine-treated, steroid-treated, and control groups, respectively. In summary, there was no significant difference between diatrizoate meglumine and steroids in their treatment efficacy on sudden deafness(p>.05).

Keywords: Sudden deafnessDiatrizoate meglumineSteroidsTreatment efficacy.
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