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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 37(5); 1994 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1994;37(5): 872-7.
Screening Value of Immunoserologic Studies in Sudden Sensorineural Hearing Loss
Kang Pyo Hong, MD, Kwon Hyung Lee, MD, Byung Joon Baek, MD, Byung Don Lee, MD, Hyuck Soon Chang, MD, and Ju Won Kang, MD
Department of Otolaryngology, College of Medicine, Soonchunhyang University, Seoul, Korea
돌발성 난청 환자에서 면역혈청학적 조사의 의의
홍강표 · 이권형 · 백병준 · 이병돈 · 장혁순 · 강주원
순천향대학교 의과대학 이비인후과학교실

The causes of sudden sensorineural hearing loss are still obscure in spite of many studies. Since McCabe's first description of autoimmune sensorineural hearing loss in 1979, there were several reports of Immunologic study in inner ear diseases by many authors. For the significance of sudden sensorineural hearing loss and autoimmune sensorineural hearing loss, the authors studied 16 patients who were diagnosed as a sudden sensorineural hearing loss about immunologic assay including erythrocyte sedimentation rate(ESR), C-reactive protein, rheumatoid factor, VDRL, immunoglobulin and complements. The following results were obtained. 1) ESR was increased in 31.3% of cases. 2) C-reactive protein and rheumatoid factor were responded in 18.8%, 12.5% of cases each. 3) Ig E was elevated in 31.3% of cases. 4) C4 was elevated in 6.3% of cases, and C1q was decreased level in 81.3% of cases. 

Keywords: Sensorineural hearing lossImmunologic studies.
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