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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 38(3); 1995 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1995;38(3): 334-44.
Ultrastructure of the Middle Ear Mucosa in Otitis Media with Effusion
Kyunghoe Hur, MD, and Hak Hyun Jung, MD
Department of Otolaryngology-Head and Neck Surgery College of Medicine, Korea University, Seoul, Korea
삼출성중이염에서 중이점막의 전자현미경적 관찰
허경회 · 정학현
고려대학교 의과대학 이비인후-두경부외과학교실

There are many factors contributing to the etiology of otitis media with effusion, and none of them is actually proven to be true. The mechanism of fluid accumulation in the middle ear is thought to be caused by Eustachian tube obstruction or impairments in the mucociliary function of the tubotympanic. The purpose of this study was to investigate the morphologic changes of the middle ear mucosa in 10 children with otitis media with effusion using the trasmission electron microscopy. Middle ear mucosa was taken as the biopsy specimen during the ventilation tube insertion. We observed only a few number of ciliary abnormalities, but a significant decrement in the number of ciliated cells with increased secretory and increased thickness of mucous layer within the mucous blanket was identified. Therefore, a decreased number of ciliated cells and increased thickness of the mucous layer may cause mucociliary dysfunction in otitis media with effusion.

Keywords: Otitis media with effusionMucous blanketCilia.
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