Ultrastructure of Nasal Mucosa in Chronic Paranasal Sinusitis |
Hye Yong Lee, MD, Yu Sung Won, MD, Han Sung Chang, MD, He Ro Yoon, MD, and Byung Do Suh, MD |
Department of Otolaryngology, Catholic University Medical College, Seoul, Korea |
만성 부비동염에서 비점막의 형태 변화에 관한 전자현미경적 연구 |
이혜용 · 원유성 · 장한성 · 윤희로 · 서병도 |
가톨릭대학교 의과대학 이비인후과학교실 |
|
|
|
ABSTRACT |
Dysfunction of mucociliary clearance system develops the pooling of nasal secretion in the nasal cavity and is a common cause of vicious cycle of symptoms in chronic paranasal sinusitis. So, we investigated the morphological changes of nasal mucosa in chronic paranasal sinusitis using light and transmission electron microscopy(TEM). The nasal mucosa was taken at bulla ethmoidalis during endoscopic sinus surgery sized in 5×5mm. The light and electron-microscopic examination of specimens showed increased number of goblet cells, non-ciliated cells, submucosal glands and inflammatory cells, decreased number of ciliated cells, deformation of cilia, and metaplasia in nasal epithelial lining and so on. Therefore, decreased numbers of ciliated cells and increased thickness of mucous layer might cause the mucociliary dysfunction in chronic paranasal sinusitis.
|
Keywords:
Chronic paranasal sinusitisㆍNasal mucosaㆍTransmission electron microscopy. |
|