Since antibiotics therapy started, osteomyelitis of the frontal bone has been decreased in incidence and has been reported as a rare disease. A case of osteomyelitis of the frontal bone associated with acute frontal sinusitis which has recently experienced was diagnosed by careful physical examination, X-ray and clinical course, and was cured by massive antibiotics therapy and drainage of the frontal sinus. This paper was attempted to report the case with a brief review of reference.