The nasopharyngeal angiofibroma is largely limited to the adolescent males. The tumor was called as ""histologically benign but clinically malignant tumor"", because of its surgically difficult site of origin, the nasopharynx, strongly invasive properties into neighboring structures, and massive bleeding tendency during operation due to its high vascularity. With successive operation, the prognosis of this tumor is relatively good. Recently, the author experienced an inoperable case of 53-years-old male with a huge nasopharyngeal angiofibroma, which was widely invaded into nasal cavity and soft and hard palates. In this report, the authors describe about the patient with several reviews of literatures.