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Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1989;32(1): 85-92. |
Non-Hodgkin's Lymphoma of the Head and Neck |
Jin Kyo Choi, MD, Kwang Suk Kim, MD, Soon Girl Hong, MD, June Sik Park, MD, and Chang Sup Seong, MD |
Department of otolaryngology, College of Medicine, Kyungpook National University, Korea |
두경부의 비호지킨 임파종 |
최진교 · 김광석 · 홍순걸 · 박준식 · 성창섭 |
경북대학교 의과대학 이비인후과학교실 |
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ABSTRACT |
Thirty one cases of non-Hodgkin's lymphoma of the head and neck were reviewed. An analysis is presented of the histopathologic and clinical features of these patients which treated in the Kyungpook University Hospital between June 1983 and May 1987. The mean age was 48.7 years, with a male to female ratio of 1.4 to 1.0 in favor of males. The peak incidence was during the fourth to sixth decades. On admission, neck mass was the most frequent symptom in 21 cases(67.7%) and dysphagia, sore throat, lump in throat and nasal stuffiness were commonly presented. The anatomical distribution was as follows: Waldeyer's ring in 22 cases(71.0%) ; nasal cavity in 1 case(3.2%) ; nodal lymphoma in 8 cases(25.8%). Within Waldeyer's ring, palatine tonsil was the most frequent site in 17 cases(77.3%), nasopharynx in 3 cases(13.6%) and base of tongue in 2 cases(9.1%). Alll biopsies were histologically classified according to the criteria of Rappaport and staged according to the Ann Arbor Classification. There were 18 poorly differentiated lymphocytic lymphomas(58.1%), 10 histiocytic lymphomas(32.3%), 2 well differentiated lymphocytic lymphomas(6.5%) and 1 mixed lymphoma(3.2%). Nineteen percent of all cases presented with disease localized to the site of origin(stage I) ; 61% had extension to regional nodes(stage II) and 20% had generalized disease(stage III & IV). In terms of treatment, 3 cases of stage I and 1 case of stage II diseases were treated with radiation therapy, 2 cases of stage III and 1 case of stage IV diseases were treated with combination chemotherapy and 2 cases of stage I, 12 cases of stage II and 1 case of stage III diseases were treated with combined therapy.
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