Three Cases of Cicatricial Pemphigoid on Upper Aerodigestive Tract |
Seung Sook Paeck, MD1, Kang Oh Lee, MD1, Boo Hyun Nam,MD1, Chan Il Park, MD1, and Kwang Sun Suh, MD2 |
1;Department of Otolarygology & 2;Aatomic Pathology, College of Medicine, Chungnam National University, Daejeon, Korea |
상기도소화기계점막에 발생한 반흔성유천포창 3례 |
백승숙1 · 이강오1 · 남부현1 · 박찬일1 · 서광선2 |
충남대학교 의과대학 이비인후과학교실1;해부병리학교실2; |
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ABSTRACT |
Cicatricial pemphigoid is a chronic bullous disease which may involve the conjunctiva, oral cavity, pharynx, larynx, nasal cavity, esophagus, trachea, genitalia and skin. The etiology remains unknown, but the presence of autoantibodies to the subepithelial basement membrane suggests an autoimmune disease. Histologic examination using an immunofluorescent stain is a critical step in diagnosis of cicatricial pemphigoid in which characteristic subepithelial cleft formation with an immune complex deposit at the basement membrane is seen. We are reporting three cases of cicatricial pemphigoid with our clinical experiences and review of literatures.
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Keywords:
Cicatricial pemphigoidㆍImmunofluoescent stain. |
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