Castleman’s disease a is heterogeneous disorder of unclear etiology. Depending on histologic and clinical findings, it has been divided into two distinct histologic subtypes, the hyaline-vascular type and plasma-cell type. The hyaline-vascular variant presents as only an asymptomatic mass; the plasma-cell type compromises only 9% of total cases and is more likely to present with constitutional symptoms. It commonly involves the mediastinal and pulmonary lymph nodes, with neck involvement in only 15% to 20% of cases. We present a case of an unusual neck mass secondary to Castleman’s disease that can easily be mistaken for lymphoma or tuberculosis.