Collision tumor has been defined as two histologically and morphologically different tumors simultaneously involving the same organ with a clear border. It occurs in a variety of sites including uterine cervix, stomach, lung, anorectal junction, oral cavity, and liver. But it is rare in head and neck fields. Most of the human cases are collisions between adenocarcinoma and squamous cell carcinoma, or lymphoma but collision of squamous cell carcinom and adenoid cystic carcinoma is also quite unusual. Squamous cell carcinoma is by far the most common histopathologic diagnosis in laryngeal malignancy, accounting for 90-95% of all cases. Other malignancies do occur, although infrequently. The adenoid cystic carcinoma of the larynx is very rare and its clinical behavior mimics adenoid cystic carcinoma elsewhere. We experienced a case of collision tumor composed of squamous cell carcinoma and adenoid cystic carcinoma in 52 year-old male patient who received total laryngectomy and bilateral neck dissection due to transglottic squamous cell carcinoma.
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