Relapsing polychondritis is a relatively rare systemic disease characterized by recurrent episode of inflammatory necrotic changes involving cartilagenous tissue of ear, nose, upper respiratory tract and peripheral joint. It has been suggested that autoimmunity against cartilagenous antigens may play a mojor role of pathogenesis of the disease and immunosuppressive treatment can reduce the severity of the illness. We are going to report our experience of a case of relapsing polychondritis associated with bilateral sensorineural hearing loss.