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Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1991;34(4): 732-736. |
Composition of glycoproteins in goblet cells and submucosal glands. |
Joo Heon Yoon, Jeung Gweon Lee, In Yong Park, Mi Sook Chang |
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상피층 배세포와 고유층 선조직의 당단백질 구성에 관한 연구 |
윤주헌 · 이정권 · 박인용 · 장미숙 |
연세대학교 의과대학 이비인후과학교실 |
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ABSTRACT |
The sources of glycoproteins in nasal secretion were goblet sells and submucosal acini of nasal mucosa. But few studies had tried to quantify them. The purpose of this study is to quantify goblet cells and acini of submucosal glands contained various glycoproteins in the inferior turbinate by using AB(pH 2.5 and 1.0)-PAS staining method in normal subjects. The results were as follows ; 1) The total number of submucosal acini was 72.1±38.3/mm2. The number of acini positive for acidic glycoproteins was 20.9±16.4/mm2 and that positive for neutral glycoproteins was 5.3±5.0/mm2. 2) The total number of goblet cells was 94.6±3.4/mm. The number of goblet cells positive for acidic glycoproteins was 83.2±3.6/mm and that positive for neutral glycoproteins was 11.4±3.0/mm. 3) Most of submucosal acini had neutral glycoproteins(71%) but most of goblet cells had acidic glycoproteins(87.9%), especially sulphomucin(81.8%). From these results, it was suggested that goblet cells and mucous acini might have different function although they were similar morphologically.
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